Monophasic sarcomatoid eccrine porocarcinoma. Report of a case and literature review.

Sarcomatoid porocarcinoma (SP) is a rare subtype of porocarcinoma composed of both malignant epithelial and sarcoma-like components. To our knowledge, only eight cases of this neoplasm have been published, all of them biphasic. A 42-year-old man presented with a latero-cervical nodule that had been noted for about five months. Histopathological study revealed an infiltrative tumor within the dermis and hypodermis without connection to epidermis, whose diagnosis was monophasic sarcomatoid eccrine porocarcinoma (SEP). The study of nine cases de SP, including the present, revealed that the ages of the patients ranged from 42 to 89 years (mean 72.3 years). There was no clear difference in the incidence with respect to gender. The location of the tumor was most common in the head and neck, followed by lower extremity. The size ranged from 2.5 cm to 3.5 cm (mean 3 cm). At the time of diagnosis, six (66.7%) lesions were ulcerated. No case was clinically diagnosed. Residual poroma was present in six (66.7%) cases. Only one case showed apocrine differentiation. Mitoses and comedonecrosis were frequent. Of the cases published, only four had a follow-up of at least 16 months. One patient succumbed to the tumor. We report for the first time a case of monophasic SEP without epidermal connection. The patient presented a regional lymph node metastasis three months after excision. The main differential diagnosis includes primary dermal melanoma and other rare variants of cutaneous melanoma, primary cutaneous clear cell sarcoma, primary cutaneous synovial sarcoma, and cutaneous metastasis from visceral sarcomatoid carcinoma.

Mandibular solitary plasmocytoma of the jaw: A case report

Plasma cell tumors are lymphoid neoplasms with an uncontrolled proliferation of B cells. These are divided intolocalized forms (solitary bone plasmocytoma -SBP- and extramedullary plasmocytoma -EP-) and disseminatedforms (multiple myeloma–MM-). The SBP is a rare and controversial disease. The aim of this article is the analysisof this entity based on the presentation of a 64-year-old man without previous medical history, with a mass in theleft mandibular angle extending to the parotid region on the same side. The panoramic radiography, computedtomography and magnetic resonance imaging showed an osteolytic lesion 6.5 x 5 x 6.7 cm in the mandibularangle with infiltration of the masticator space and left parotid region. The normality of the extension study, andhistopathological examination confirmed the diagnosis of SBP. The patient received treatment with radiotherapywith good outcome (AU)

Carcinoma ex adenoma parotídeo: a propósito de un caso / No disponible

No disponible

Localized eosinophilic (Langerhans' cell) granuloma of the lower lip. A lesion that may cause diagnostic error.

Eosinophilic (Langerhans' cell) granuloma is most common in children and is unusual in the elderly. A cutaneous lesion as the sole manifestation of adult Langerhans' cell histiocytosis is rare. We report an 81-year-old man who presented with a noduloulcerative lesion on the lower lip. A punch biopsy suggested a lymphoepithelioma-like carcinoma. In the absence of immunohistochemistry, the large pale cells with atypical lobular nuclei and patent nucleoli, with an overlying ulceration, were interpreted as carcinoma cells. Definitive diagnosis was established after complete resection of the lesion aided with the use of immunohistochemistry. The proliferating cells were S100, CD1a and CD207 (langerin) positive and cytokeratin, epithelial membrane antigen, CD15, CD30, melan A and carcinoembryonic antigen negative. To our knowledge, eosinophilic (Langerhans' cell) granuloma of the lip has not been described. The case constituted a diagnostic challenge because of its unusual clinical presentation and its histopathological similarity to certain other benign and malignant entities. Because there was no other organ involved, the patient was treated with complete surgical excision without recurrence or other organ involvement in the 4-month follow-up period. Labial eosinophilic (Langerhans' cell) granuloma should be considered in the histological differential diagnosis in cases with atypical polymorphous infiltrates including large pale cells.

Carcinoma oral de células escamosas. Parámetros citométricos de interés pronóstico / Oral squamous cell carcinoma. Cytometric parameters of prognostic interest

Objetivos: el presente estudio se realizó para encontrar posiblesfactores pronósticos del Carcinoma oral de células escamosaspuesto que es una enfermedad frecuente ( 3 – 4 % de los tumoresmalignos ) que origina una gran morbilidad y mortalidad y quejustifica cualquier intento que trate de aportar algo para conocermejor esta patología. Diseño del estudio: hemos realizadoun estudio sobre 81 carcinomas orales de células escamosasextraídos del archivo del Hospital Universitario Marqués deValdecilla ( Santander ) , tratados con el mismo procedimiento, de los cuales en 67 de ellos se realizó citometría de flujo.Resultados: No hemos encontrado diferencias estadísticamentesignificativas entre el índice de proliferación celular y el índicemitótico , la ploidía y la fase S. Así mismo ninguna de lasvariables citométricas estudiadas ha presentado relación conla aparición de recidiva loco-regional , metástasis a distanciani con la supervivencia.Conclusiones: no podemos utilizar éstas variables como factor pronósticoen el carcinoma de células escamosas de la cavidad oral

Objectives: the present study was made in order to find possibleprognostic factors in oral squamous cell carcinoma, given thatit is a frequent disease (3-4% of all malignant tumors) and isthe cause of a high morbidity and mortality which justifies anyattempt to contribute something towards the understanding ofthis pathology.Study design: 81 oral squamous cell carcinomas, treated with thesame procedure, and retrieved from the archive of the HospitalUniversitario Marqués de Valdecilla (Santander) were studied.Flow cytometry was carried out on 67 of the samples.Results: no statistically significant differences were foundbetween the cellular proliferative index and the mitotic index,ploidy and the S-phase factor. Likewise, none of the cytometricvariables studied presented any association with the appearanceof local relapse, distant metastases or survival.Conclusions: these variables cannot be used as a prognosticfactors in squamous cell carcinomas of the oral cavity

Oral squamous cell carcinoma. Cytometric parameters of prognostic interest.

OBJECTIVES: The present study was made in order to find possible prognostic factors in oral squamous cell carcinoma, given that it is a frequent disease (3-4% of all malignant tumors) and is the cause of a high morbidity and mortality which justifies any attempt to contribute something towards the understanding of this pathology. STUDY DESIGN: 81 oral squamous cell carcinomas, treated with the same procedure, and retrieved from the archive of the Hospital Universitario Marqués de Valdecilla (Santander) were studied. Flow cytometry was carried out on 67 of the samples. RESULTS: No statistically significant differences were found between the cellular proliferative index and the mitotic index, ploidy and the S-phase factor. Likewise, none of the cytometric variables studied presented any association with the appearance of local relapse, distant metastases or survival. CONCLUSIONS: These variables cannot be used as a prognostic factors in squamous cell carcinomas of the oral cavity.

Cóndilo bífido: a propósito de un caso / Bifid condyle: case report

En este artículo, a propósito de un caso clínico, se presenta elcóndilo bífido como una rara alteración mandibular con muchasincógnitas. Su diagnóstico suele ser un hallazgo casual en radiografíaspanorámicas de rutina. El número de casos relatados enliteratura ha experimentado en los últimos años un crecimientodebido al aumento de pruebas radiológicas que se realizan. Sediscute sobre las diferentes teorías existentes con respecto a laetiología de este proceso. En lo referente a la relevancia clínicadel cóndilo bífido señalamos que la gran mayoría son asintomáticos.Es importante realizar un buen diagnóstico diferencialde éste proceso con otras lesiones que producen alteracionesmorfológicas condilares, la prueba de elección es la tomografíacomputerizada. El tratamiento conservador suele ser efectivo enlos casos con clínica de disfunción articular leve, la cirugía tansólo suele indicarse en casos de anquilosis condilar, normalmenteéstos casos son secundarios a traumatismos

The double headed mandible condyle is a rare alteration that isfrequently diagnosticated as an incidental finding in a panoramicradiograph. The different theories about its etiology areexplained in this article. Symptoms described with bifid condylesvary from case to case, but in most instances are absent.Computer tomography is the ideal imaging method to evaluatethe condyle morphology and to role out any degenerative processto achieve the differential diagnosis. Treatment is conservativefor symptomatic patients with TMJ disorders, surgical treatmentis described in literature in TMJ ankylosis that develops in bifidcondyles secondary to trauma

Bifid condyle: case report.

The double headed mandible condyle is a rare alteration that is frequently diagnosticated as an incidental finding in a panoramic radiograph. The different theories about its etiology are explained in this article. Symptoms described with bifid condyles vary from case to case, but in most instances are absent. Computer tomography is the ideal imaging method to evaluate the condyle morphology and to role out any degenerative process to achieve the differential diagnosis. Treatment is conservative for symptomatic patients with TMJ disorders, surgical treatment is described in literature in TMJ ankylosis that develops in bifid condyles secondary to trauma.